Tapentadol is used to treat several types of pain (Tapentadol Interactions) with less adverse effects. If you are planning to use tapentadol to get relief from pain, the you should know about the risks involved in tapemtadol interactions. Because like all other medicines tapentadol also has the ability to interact to other medicines and lead unwanted side effects. In this article we shed light on the risks of tapentadol drug interactions.
Tapentadol Facts
Tapentadol is a prescription opioid pain reliever used to treat moderate to severe pain. Pain is an unpleasant sensation caused by actual or potential tissue damage.Tapentadol inhibits the way neurons communicate pain between the brain and the body by acting directly on opioid receptors in the central nervous system.
Tapentadol is a pain reliever that is prescribed by doctors whenever you are in pain. Tapentadol should only be used as prescribed by a doctor. Because Tapentadol belongs to the opioid class of drugs, self-administration may result in drug addiction and dependence.
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Tapentadol drug interactions:
Tapentadol, as a potent opioid analgesic, has the potential to interact with other medications, causing side effects or altering their effectiveness. The following are some of the main drug interactions og tapentadol:
- When you take tapentadol along with other CNS depressants, such as benzodiazepines, sedatives, tranquilizers, or alcohol, it may causes drowsiness, respiratory depression, and an increased risk of overdose.
- Tapentadol should not be used along with MAOIs or within 14 days of discontinuing MAOIs.Because this drug interaction has the ability to cause serotonin syndrome which is a deadly condition associated with symptoms like agitation, hallucinations, irregular pulse, fever, and muscular pain.
- Tapentadol can increase the risk of serotonin syndrome when taken with other serotonergic drugs such as selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs). If you need take both the medicines simultaneously take suggestions from your doctor regarding the safety precautions.
- Some antidepressants and antipsychotics drugs, particularly those with strong serotonergic effects, may interact with tapentadol and increase the risk of serotonin syndrome. When taking tapentadol with these medications,doctors should analyse the ration of advantages and disadvantages and should intimate to their patients before using those medicines.
- After entering into the body Tapentadol will be metabolised by cytochrome P450 (CYP450) enzymes, particularly CYP2D6 and CYP3A4. Medicines which inhibits or stimulates these enzymes can affect tapentadol metabolism and clearance of tapentadol from body.
- Never take Tapentadol along with opioid antagonists such as naloxone or naltrexone because they will decrease the effectiveness of Tapentadol effects and trigger withdrawal symptoms in opoid dependent people.
These are some of the major drug-drug interactions of tapanetadol the risks associated with those interactions. Before your start using tapentadol intimate to your physician if you are using any of the above mentioned medicines.
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Precautions to be taken while using Tapentadol:
While Tapentadol can give effective pain relief, it is also important to take the following precautions to get maximum result (Pain relief) with less or no adverse effects.
- Several precautions must be taken when taking Tapentadol. Inform your doctor your present treatments (if any), medical conditions, or medicines you are using for other disorders.
- It is essential to follow the recommended dosage and avoid taking higher doses of it without consulting a doctor.
- If you have a history of tapentadol abuse or addiction, it is essential to discuss it with your healthcare provider.
- People who are having respiratory issues must use Tapentadol very carefully. Because tapentadol may cause respiratory problems.
- Also be cautious while using tapentadol in case if you are suffering with liver or kidney diseases.
- Pregnant or breastfeeding women should consult their doctor before taking tapentadol to get relief from pain.because the effects tapentadol on pregenant and breastfeeding woman is unclear.
- Dont stop taking tapentadol suddenly because sudden stoppage may cause withdrawal symptoms.
Also Read: How to relate Tapentadol with Neuropathic Pain and Opioid drugs?
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